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Molecular imaging in a (pre-) clinical context

Journal Volume 71 - 2008
Issue Fasc.3 - Symposium
Author(s) Norbert Lange, Christoph D. Becker, Xavier Montet
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(1) Laboratory of Pharmaceutics and Biopharmaceutics, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Switzerland ; (2) Radiology department, Geneva University Hospital and University of Geneva, Geneva, Switzerland.

Molecular imaging can be defined as imaging of biological processes in a living organism at the molecular and/or cellular level. To achieve this goal, genetic information and new chemistries have to be combined into new imaging probes detectable by sophis- ticated imaging techniques. In contradistinction to conventional imaging, which mostly detects architectural, or morphological dis- tortions (a late event), molecular imaging should be able to detect molecular changes that are at the basis of diseases. The detection of subtle pathologic changes in early, asymptomatic disease should have a tremendous impact on healthcare as a whole. (Acta gastro- enterol. belg., 2008, 71, 308-317).

© Acta Gastro-Enterologica Belgica.
PMID 19198577